Academic Qualifications

Professor (since 2011),    College of Veterinary Medicine, South China Agricultural University

1992   B.S.   Nanjing Agricultural University - Veterinary Medicine

1998   M.S.   South China Agricultural University - Veterinary Medicine 

2001   Ph.D.  South China Agricultural University - Veterinary Medicine

Research Interests

1  Pharmacokinetics/pharmacodynamics of antimicrobial agents in animals

2  Residue depletion and risk assessment of veterinary drugs in food animals

3  Metabolism of drugs in animals

Selected Publications

Nan Zhang, Yuzhi Wu, Huanzhong Ding（correspongding author）. The PK-PD Relationship and Resistance Development of Danofloxacin against Mycoplasma gallisepticum in An in vivo Infection Model. Frontiers in microbiology. May 2017 | Volume 8 | Article 926.  doi: 10.3389/fmicb.2017.00926 (SCI二区, IF=4.165)

Zhang, Nan; Ye, Xiaomei; Wu, Yuzhi, Ding, HZ（correspongding author）. Determination of the Mutant Selection Window and Evaluation of the Killing of Mycoplasma gallisepticum by Danofloxacin, Doxycycline, Tilmicosin, Tylvalosin and Valnemulin. PLOS ONE，2017: 12（1），DOI:10.1371/journal.pone.0169134

Mingpeng Xiong, Xun Wu, Xiaomei Ye, Longfei Zhang, Shuyi Zeng, Zilong Huang, Yuzhi Wu, Jian Sun, Huanzhong Ding（correspongding author）. Relationship between Cefquinome PK/PD Parameters and Emergence of Resistance of Staphylococcus aureus in Rabbit Tissue-Cage Infection Model. Frontiers in Microbiology，2016，7：874. doi: 10.3389/fmicb.2016.00874

Nan Zhang,Xiaoyan Gu,Xiaomei Ye,Xun Wu,Bingxu Zhang,Longfei Zhang, Xiangguang  Shen,Hongxia  Jiang and Huanzhong Ding（correspongding author）. The PK/PD Interactions of Doxycycline against Mycoplasma gallisepticum. Frontiers in Microbiology，2016，7：653. doi: 10.3389/fmicb.2016.00653

Li Y, Feng B, Gu X, Yang D, Zeng Z, Zhang B and Ding H.（correspongding author）  Correlation of PK/PD Indices with Resistance Selection for Cefquinome against Staphylococcus aureus in an In Vitro Model. Front. icrobiol， 2016，7:466. doi: 10.3389/fmicb.2016.00466

Mengxiao Gu, Nan Zhang, Longfei Zhang, Mingpeng Xiong, Yuanyuan Yang, Xiaoyan Gu, Xiangguang Shen and Huanzhong Ding* . Response of a clinical Escherichia coli strain to repeated cefquinome exposure in a piglet tissue-cage model. BMC Veterinary Research , 2015, 11:169  doi:10.1186/s12917-015-0486-6

Li, YF; Wang, L; Gu, XY; Zeng, ZL; He, LM; Yang, F; Yuan, B; Shu, JH ; Ding, HZ（correspongding author） . Pharmacokinetics and Residues of Cefquinome in Milk of Lactating Chinese Dairy Cows After Intramammary Administration. JOURNAL OF INTEGRATIVE AGRICULTURE, 2014, 13(12): 2750-2757 

Zhang, BX; Lu, XX; Gu, XY; Li, XH; Gu, MX; Zhang, N; Shen, XG; Ding, HZ （correspongding author）. Pharmacokinetics and ex vivo pharmacodynamics of cefquinome in porcine serum and tissue cage fluids. VETERINARY JOURNAL, 2014, 199(2):399-405 

Zhang, B; Gu, X; Li, X; Gu, M; Zhang, N; Shen, X; Li, Y; Ding, H（correspongding author）. Pharmacokinetics and ex-vivo pharmacodynamics of cefquinome against Klebsiella pneumonia in healthy dogs. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2014, 37(4): 367-373 

Zhang, BX, Gu XY, Li YF, Li XH, Gu MX, Zhang N, Shen XG, Ding HZ（correspongding author）. In vivo evaluation of mutant selection window of cefquinome against Escherichia coli in piglet tissue-cage model. BMC VETERINARY RESEARCH, 2014, 10:297

Shan, Q; Yang, F; Wang, J; Ding, H; He, L; Zeng, Z . Pharmacokinetic/pharmacodynamic relationship of cefquinome against Pasteurella multocida in a tissue- cage model in yellow cattle. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2014, 37(2): 178-185 

Wang, J; Shan, Q; Ding, HZ; Liang, CP; Zeng, ZL.  Pharmacodynamics of Cefquinome in a Neutropenic Mouse Thigh Model of Staphylococcus aureus Infection. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58(6): 3008-3012 

Shu, JH; He, LM; Ding, HZ; Wang, LQ; Guo, HY ; Gao, Y; Dzakah, EE; Zeng, ZL.  Synthesis of furaltadone metabolite, 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ) and novel haptens for the development of a sensitive enzyme-linked immunosorbent assay (ELISA). ANALYTICAL METHODS, 2014, 6(7): 2306-2313 

Ding H., Wang L., Shen X., Gu X., Zeng D., Zeng Z.  Plasma and tissue pharmacokinetics of marbofloxacin in experimentally infected chickens with Mycoplasma gallisepticum and Escherichia coli, JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2013，Volume: 36   Issue: 5   Pages: 511-515

Yafei Li, Ning Zhao, Zhenling Zeng, Xiaoyan Gu, Binghu Fang, Fan Yang, Bingxu Zhang,  Huanzhong Ding（correspongding author）.  Tissue Deposition and Residue Depletion of Cyadox and Its Three Major Metabolites in Pigs after Oral Administration, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2013, 61, 9511 9510−9515

ZHAO Ning, WANG Lin, LU Xiao-xiong, JIA Hui-qin, FANG Bing-hu, ZENG Zhen-ling and DING Huanzhong（correspongding author）. Pharmacokinetics of Cyadox and Its Major Metabolites in Swine after  Intravenous and Oral Administration, JOURNAL OF INTEGRATIVE AGRICULTURE, 2013, 12(3): 495-501

Ding Huanzhong; Liu Yingchun; Zeng Zhenling; et al. Pharmacokinetics of mequindox and one of its major metabolites in chickens after intravenous, intramuscular and oral administration. RESEARCH IN VETERINARY SCIENCE,2012.(93)2，374-377

Wang, A; Ding, HZ; Liu, YM; Gao, Y; Zeng, ZL . Single dose pharmacokinetics of terbinafine in cats. JOURNAL OF FELINE MEDICINE AND SURGERY, 2012, 14(8): 540-544 

Zhong, JL ; Zhang, GJ ; Shen, XG ; Wang, L ; Fang, BH ; Ding, HZ （correspongding author）. Pharmacokinetics of Quinocetone and Its Major Metabolites in Swine After Intravenous and Oral Administration. AGRICULTURAL SCIENCES IN CHINA，ISSN1671-29272011.(10)8，: 1292-1300

Zeng, Z ; Deng, G ; Shen, X ; Rizwan-ul-Haq, M ; Zeng, D; Ding, H （correspongding author）. Plasma and tissue pharmacokinetics of danofloxacin in healthy and in experimentally infected chickens with Pasteurella multocida. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS， 2011，(34)1: 101-104

Ding H.; Li Y.; Chen Z.; et al. Plasma and tissue cage fluid pharmacokinetics of marbofloxacin after intravenous, intramuscular, and oral single-dose application in pigs. Journal of Veterinary Pharmacology and Therapeutics，2010（33）5: 507-510

Zeng, Z ; Wu, J; Yang, G ; Chen, Z ; Huang, X ; Ding, H（correspongding author）. Study of colistin depletion in duck tissues after intramuscular and oral administration. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS，2010，(33 )4: 408-410

Ding H. Z.; Yang G. X.; Huang X. H.; et al. Pharmacokinetics of difloxacin in pigs and broilers following intravenous, intramuscular, and oral single-dose applications. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS， 2008(31 )3 : 200-204

Fu, LX; Jiang, ZG; Ding, HZ ; Liu, YH . Population pharmacokinetics of enrofloxacin and its active metabolite ciprofloxacin in ill cows. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2008, 31(3): 240-245 

Ding H. Z.; Zeng Z. L.; Fung K. F . Pharmacokinetics of sarafloxacin in pigs and broilers following intravenous, intramuscular, and oral single-dose applications. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2001, 24(5) : 303-308