来源:beat365 发布时间:2023-11-20 浏览次数:13744
孙海亮,男,1980年出生于山东潍坊,博士,副教授,硕士生导师。
2016年10月至今beat365首聘副教授、副教授
2014年9月至2016年6月美国密西西比州立大学beat365研究助理教授(Faculty)。
2011年9月至2014年9月美国密西西比州立大学beat365博士后 (Staff) 。
2011年6月 beat365预防兽医专业,获博士学位。
2008年6月 甘肃农业大学beat365预防兽医专业,获硕士学位。
2005年6月 河南农业大学牧医工程学院动物医学专业,获学士学位。
流感病毒等禽重要病毒病的遗传演化、抗原变异、致病性、传播机制、新型疫苗研发、病毒免疫、新发传染病研究
1. 主持十四五国家重点研发计划子课题:禽重要病毒病mRNA疫苗创制,50万;
2. 主持广东省自然科学基金:受体嗜性改变推进H9N2 AIV抗原变异,10万;
3. 主持广东省自然科学基金:EBBP蛋白调节SQSTM1-NRF2-KEAP1轴影响禽流感病毒复制的分子机制,10万;
4. 主持广东省教育厅特色创新项目:猪H1亚型流感病毒耐酸性增强的分子基础, 15万;
5. 主持横向课题:禽腺病毒通用性抗体研制 ,20万;
6. 主持华南农业大学启动基金 20万;
7.参与国家自然科学基金重点项目1项(排名第4),H9N2亚型禽流感病毒激活鸡T细胞免疫应答的分子机制,285万; 8. 参与国家重点研发计划子项目1项(排名第2),水禽疫苗细胞悬浮培养、细菌高密度发酵、耐热保护剂等关键新工艺研究与应用,52万。
1. Liu Y, Wei Y, Zhou Z, Gu Y, Pang Z, Liao M, Sun H. Overexpression of TRIM16 Reduces the Titer of H5N1 Highly Pathogenic Avian Influenza Virus and Promotes the Expression of Antioxidant Genes through Regulating the SQSTM1-NRF2-KEAP1 Axis. Viruses 2023; 15.
2. Liu H, Pang Z, Liu Q, Sun H, Liao M. 2022 outbreak of human mpox: Dissemination and evolution dynamic. Journal of medical virology 2023; 95:e28744.
3. Sun H, Wang Y, Liu H, Pang Z, Cui X, Zhao R, Liu Y, Qu X, Huang M, Ke C, Liao M. The genetic diversity, replication, and transmission of 2009 pandemic H1N1 viruses in China. Frontiers in microbiology 2023; 14:1110100.
4. Sun H, Wang A, Wang L, Wang B, Tian G, Yang J, Liao M. Systematic Tracing of Susceptible Animals to SARS-CoV-2 by a Bioinformatics Framework. Frontiers in microbiology 2022; 13:781770.
5. Sun H, Liu H, Liu Y, Pang Z, Jiang Y, Liu Q, Liao M. Genetic characterization of a novel quadruple reassortant influenza A (H1N2) virus from swine, China, 2021. The Journal of infection 2022.
6. Li S, Zhao R, Yang Q, Wu M, Ma J, Wei Y, Pang Z, Wu C, Liu Y, Gu Y, Liao M, Sun H. Phylogenetic and pathogenic characterization of current fowl adenoviruses in China. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2022; 105:105366.
7. Liu H, Wu C, Pang Z, Zhao R, Liao M, Sun H. Phylogenetic and Phylogeographic Analysis of the Highly Pathogenic H5N6 Avian Influenza Virus in China. Viruses 2022; 14.
8. Wu M, Su R, Gu Y, Yu Y, Li S, Sun H, Pan L, Cui X, Zhu X, Yang Q, Liu Y, Xu F, Li M, Liu Y, Qu X, Wu J, Liao M, Sun H. Molecular Characteristics, Antigenicity, Pathogenicity, and Zoonotic Potential of a H3N2 Canine Influenza Virus Currently Circulating in South China. Frontiers in microbiology 2021; 12:628979.
9. Yu Y, Wu M, Cui X, Xu F, Wen F, Pan L, Li S, Sun H, Zhu X, Lin J, Feng Y, Li M, Liu Y, Yuan S, Liao M, Sun H. Pathogenicity and transmissibility of current H3N2 swine influenza virus in Southern China: A zoonotic potential. Transboundary and emerging diseases 2021.
10. Liu Y, Li S, Sun H, Pan L, Cui X, Zhu X, Feng Y, Li M, Yu Y, Wu M, Lin J, Xu F, Yuan S, Huang S, Sun H, Liao M. Variation and Molecular Basis for Enhancement of Receptor Binding of H9N2 Avian Influenza Viruses in China Isolates. Frontiers in microbiology 2020; 11:602124.
11. Sun H, Lin J, Liu Z, Yu Y, Wu M, Li S, Liu Y, Feng Y, Wu Y, Li M, Jiao P, Luo K, Liao M. Genetic, Molecular, and Pathogenic Characterization of the H9N2 Avian Influenza Viruses Currently Circulating in South China. Viruses 2019; 11.
12. Zhang X, Sun H, Cunningham FL, Li L, Hanson-Dorr K, Hopken MW, Cooley J, Long LP, Baroch JA, Li T, Schmit BS, Lin X, Olivier AK, Jarman RG, DeLiberto TJ, Wan XF. Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine. PLoS pathogens 2018; 14:e1007417.
13. Sun H, Blackmon S, Yang G, Waters K, Li T, Tangwangvivat R, Xu Y, Shyu D, Wen F, Cooley J, Senter L, Lin X, Jarman R, Hanson L, Webby R, Wan XF. Zoonotic Risk, Pathogenesis, and Transmission of Avian-Origin H3N2 Canine Influenza Virus. Journal of virology 2017; 91.
14. Sun H, Xue JL, Bailey E, Xu Y, Hu G, Baroch J, Zhang Y, Pace L, DeLiberto TJ, Wan XF. A quantitative RT-PCR assay for rapid detection of Eurasian-lineage H10 subtype influenza A virus. Virologica Sinica 2016; 31:444-7.
15. Sun H, Cunningham FL, Harris J, Xu Y, Long LP, Hanson-Dorr K, Baroch JA, Fioranelli P, Lutman MW, Li T, Pedersen K, Schmit BS, Cooley J, Lin X, Jarman RG, DeLiberto TJ, Wan XF. Dynamics of virus shedding and antibody responses in influenza A virus-infected feral swine. The Journal of general virology 2015; 96:2569-78.
16. Xu Y, Cao H, Liu H, Sun H, Martin B, Zhao Y, Wang Q, Deng G, Xue J, Zong Y, Zhu J, Wen F, Long LP, Wong SS, Zhao N, Fu X, Liao M, Hu G, Webby R, Gao GF, Wan XF. Identification of the source of A (H10N8) virus causing human infection. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2015; 30:159-63.
17. Sun H, Cui P, Song Y, Qi Y, Li X, Qi W, Xu C, Jiao P, Liao M. PB2 segment promotes high-pathogenicity of H5N1 avian influenza viruses in mice. Frontiers in microbiology 2015; 6:73.
18. Sun HL, Yang JL, Zhang T, Long LP, Jia K, Yang GH, Webby RJ, Wan XF. Using Sequence Data To Infer the Antigenicity of Influenza Virus. mBio 2013; 4.
19. Sun HL, Jiao PR, Cheng YQ, Yuan RY, Cui PF, Jin LM, Xin CA, Liao M. The Pathogenicity Variation of Two Quail-Origin H5N1 HPAV to BALB/c Mice after Six Passages in Quail. J Anim Vet Adv 2011; 10:1974-80.
20. Sun HL, Jiao PR, Jia BQ, Xu CG, Wei LM, Shan F, Luo KJ, Xin CA, Zhang KX, Liao M. Pathogenicity in quails and mice of H5N1 highly pathogenic avian influenza viruses isolated from ducks. Veterinary microbiology 2011; 152:258-65.
主讲本科生《分子生物学》、《小动物传染病学》
主讲博士研究生《英语科技论文写作与交流》
参讲本科生《禽病学》、《兽医传染病学》
参讲本科生《分子生物学实验》
参讲硕士研究生《学术规范和科研伦理》
博士生: 1名
硕士生: 15名
本科生: 4名
已毕业硕士:9名
目前有21人
副教授 1名
博士研究生 1名
硕士研究生 15名
本科生 4名