郭亚琼

郭亚琼

 学科:预防兽医学                 
电子邮件:guoyq@scau.edu.cn
通讯地址:广州市天河区五山路483号beat365510642        
更多信息:寄生虫学教研室


简介


郭亚琼,女,1988年生,副教授,博士生导师。

广东省杰出青年基金项目获得者,科技部“人兽共患寄生虫病创新研究团队”核心成员,中国畜牧兽医学会寄生虫学分会理事,广州市广州市农村科技特派员

主要从事重要人兽共患寄生虫病原隐孢子虫等的分子流行病学、比较基因组学和病原生物学研究。近五年,以第一/通讯作者在Cell Host Microbe、Mol Biol Evol、Trends Parasitol等领域内权威期刊发表论文20余篇,在Research. com 2023年动物科学和兽医学领域中国科学家榜单中排名第23。主持国家自然科学基金3项(面上2项,青年基金1项),同时也获得了广东省杰出青年基金和面上项目的资助,授权专利5项。


学历及培训经历


2010. 09-2015. 06       华东理工大学  环境科学与工程专业  博士

2012. 07-2014. 08      Centers for Disease Control and Prevention (United States)  联合培养博士 

2006 年9月-2010     年6月 郑州轻工业学院    生物工程专业   学士


工作经历


2017.07 至今                beat365    副教授

2015. 07-2017. 06       华东理工大学生物工程学院 博士后


研究领域


人兽共患寄生病原的检测及溯源

人兽共患寄生病原的比较基因组学研究

人兽共患寄生病原的致病机制研究


承担科研项目情况


国家自然科学基金面上项目:M16金属蛋白酶CpINS19对微小隐孢子虫感染力的影响及其功能位点解析,2023-2026,主持

国家自然科学基金面上项目:微小隐孢子虫入侵相关蛋白GP40和GP15的互作机制, 2020-2023,主持

国家自然科学基金青年科学基金:牛隐孢子虫的种内遗传多样性及地理隔离性研究,2017-2019,主持

十四五国家重点研发计划子课题:畜禽食源性寄生虫现场快速甄别和溯源技术研发,2023-2027,主持

广东省自然科学基金杰出青年基金项目:微小隐孢子虫宿主适应性相关毒力因子的作用机制, 2024-2027,主持

广东省自然科学基金面上项目:微小隐孢子虫宿主适应性相关毒力因子的作用机制, 2019-2022,主持

广州市基础与应用基础研究一般项目:MEDLE-1蛋白在微小隐孢子虫入侵和发育中的作用机制,2022-2024,主持


代表论著(*通讯作者)


1.Huang, Wanyi#; Guo, Yaqiong#; Lysen, Colleen#; Wang, Yuanfei; Tang, Kevin; Seabolt, Matthew H.; Yang, Fengkun; Cebelinski, Elizabeth; Gonzalez-Moreno, Olga; Hou, Tianyi; Chen,Chengyi; Chen, Ming; Wan, Muchun; Li, Na; Hlavsa, Michele C.; Roellig, Dawn M.; Feng, Yaoyu*; Xiao, Lihua*; Multiple introductions and recombination events underlie the emergence of a hypertransmissible Cryptosporidium hominis subtype in the USA, Cell Host & Microbe, 2023, 31(1): 112-123

2.Guo, Yaqiong; Ryan, Una; Feng, Yaoyu*; Xiao, Lihua*; Emergence of zoonotic Cryptosporidium parvum in China, Trends in Parasitology, 2022, 38(4): 335-343

3.Wang, Tianpeng#; Guo, Yaqiong#; Roelling, Dawn M.; Li, Na; Santín, Mónica; Lombard, Jason; Kváč, Martin; Naguib, Doaa; Zhang, Ziding*; Feng, Yaoyu*; Xiao, Lihua*; Sympatric recombination in zoonotic Cryptosporidium leads to emergence of populations with modified host preference, Molecular Biology and Evolution, 2022, 39: msac150

4.Miner Deng; Tianyi Hou; Jie Zhang; Xinjie Mao; Fuxian Yang; Yanting Wei; Yongping Tang; Wanting Zeng; Wanyi Huang; Na Li; Lihua Xiao*; Yaoyu Feng*; Yaqiong Guo*; Cultivation, cryopreservation, and transcriptomic studies of host-adapted Cryptosporidium parvum and Cryptosporidium hominis using enteroids, iScience 27, 109563

5.Yang, Xin#; Guo, Yaqiong#; Xiao, Lihua*; Feng, Yaoyu*; Molecular epidemiology of human cryptosporidiosis in low- and middle-income countries, Clinical Microbiology Reviews, 2021,34(2): e00087-19

6.Hu, Suhui; Wan, Muchun; Huang, Wanyi; Wang, Weijian; Liang, Ruobing; Su, Dongle; Li, Na; Xiao, Lihua; Feng, Yaoyu*; Guo, Yaqiong*; Age and episode-associated occurrence of Cryptosporidium species and subtypes in a birth-cohort of dairy calves, Transboundary and Emerging Diseases, 2022, 69(5): e1710-e1720

7.Feng, Kangli; Li, Na; Huang, Yujin; Chen, Chengyi; Wen, Luxing; Wang, Weijian; Ryan Una M.; Xiao, Lihua; Feng, Yaoyu*; Guo Yaqiong*; Longitudinal follow-up reveals occurrence of successive episodes of Cryptosporidium bovis and Cryptosporidium ryanae infections by different subtype families in dairy cattle, International Journal for Parasitology, 2023,53:654-661

8.Huang, Jianbo; Chen, Ming; He, Yongli; Chen, Haoyu; Huang, Mingming; Li, Na; Ryan, Una; Kváč, Martin; Feng, Yaoyu; Xiao, Lihua*; Guo, Yaqiong*; Cryptosporidium equi n. sp. (Apicomplexa: Cryptosporidiidae): biological and genetic characterizations, International Journal for Parasitology, 2023, 53:545-554

9.Jia, Ruilian; Huang, Wanyi; Huang, Ni; Yu, Zhengjie; Li, Na; Xiao, Lihua; Feng, Yaoyu; Guo, Yaqiong*; High infectivity and unique genomic sequence characteristics of Cryptosporidium parvum in China, PLoS Neglected Tropical Diseases, 2022, 16(8): e0010714

10.Li, Muxiao; Sun, Xiaohua; Chen, Haoyu; Li, Na; Feng, Yaoyu; Xiao, Lihua; Guo, Yaqiong*; Stable expression of mucin glycoproteins GP40 and GP15 of Cryptosporidium parvum in Toxoplasma gondii, Parasites & Vectors, 2024, 17: 65


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